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#sarscov2

12 posts10 participants0 posts today
Public
Broadwaybabyto

I just had a guy get angry at me for saying we’re still in a pandemic. He said it was fear mongering and “silly” to continue to take precautions.

He then went on to say his wife has Long Covid and he’s had Covid “at least 4-5 times”.

This attitude is why we’re in this mess. His own wife was disabled by Covid, and rather than adapt his behaviour he’s exposed her 4-5 additional times.

Repeat infections are devastating to those with Long Covid. Not to mention each infection does cumulative damage, and eventually you will be left disabled.

Even if you’re someone who believes it’s “just a flu”… surely you recognize people didn’t get the flu 4-5 times in a four year period? Being sick that often is an aberration, and a darn good reason to take precautions.

You know who hasn’t had COVID 4-5 times? People who are taking precautions.

Bonus tip: If you’re masking and you become infected anyways, you’ve reduced your viral load AND you’ve made sure not to infect anyone else. That’s community care & compassion and it’s worth doing.

#covidisairborne#covidisnotover#longcovid
Public
Ms. Opossum graphs COVID data.

UPDATED: #Ontario #SARSCoV2 variants.

Of 50 samples from 3/2 - 3/8:
XEC.*: 22% (⬇️ 37.6%)
LP.8.1.*: 20% (⬇️ 30.1%)
KP.3.3.2.* (incl. NP.1): 20% (⬆️ 5.8%)
LF.7.7.2: 24% (⬆️ 3.5%)

ratnegative.tumblr.com/ONVaria #COVID19

-----------

Of the samples collected in Ontario on these weeks, the prevalence of each of these significant variants/lineages are as follows:

- 3/2 - 3/8 -
• XEC.*: 22%
• JN.1.11.1.*: 48%
→ LP.8.1.* (incl. LP.8.1.1): 20%
→ KP.3.* (only KP.3.1.1.*, ".3.3.2.*): 28%
→ KP.3.1.1.* (incl. MC.1.2, ".21.1): 8%
→ KP.3.3.2.* (incl. NP.1): 20%
→ NP.1: 4%
• JN.1.16.1.* (incl. LF.7.2.1, ".7.7.2): 28%
→ LF.7.7.2: 24%

- 2/23 - 3/1 -
• XEC.*: 37.6%
• JN.1.11.1.*: 49.7%
→ LP.8.1.* (incl. LP.8.1.1.*): 30.1%
→ KP.3.* (only KP.3.1.1.*, NP.1 ctd.) †: 19.7%
→ KP.3.1.1.* (incl. MC.1.*, ".10.*, ".13.*, ".24, ".31): 13.9%
→ MC.1.* (incl. MC.1.2, ".1.6, ".1.7): 6.9%
→ KP.3.3.2.* (only NP.1 ctd.): 5.8%
• JN.1.16.1.* (incl. LF.7.2.1, ".7.7.*): 5.8%
→ LF.7.7.2: 3.5%

† 1 KP.3.3.2 & 1 KP.3.3.5 sample ctd. as JN.1.*

X.X.* in text = X.X & descendants.

X.X.* in graph = all descendants of X.X, except for ones with own segment of week’s bar.

Public
Broadwaybabyto

Mask bans are ableist, discriminatory ugly laws.

Disabled advocates have been warning for years that if people didn’t help normalize masking, bans would follow

Please call legislators in New York and tell them No mask bans!

Medical exemptions aren’t enough, everyone needs the legal right to mask

The police are not doctors. They can’t determine who’s “sick enough” to wear a mask.

Many people with invisible illnesses struggle to get healthcare workers to take us seriously. We don’t want to be questioned by police.

Everyone should be allowed to mask up to prevent covid.

BUDGET DUE MONDAY! CALL NOW! DON'T LET THEM BAN MASKS IN NY Governor Hochul is still trying to force an anti-mask law into the New York state budget - and the deadline is Monday night. Our calls are working, but we need more calls TODAY, especially from upstate NY. Now's the time to call your state reps to say NO MASK BAN. TOOLKIT FOR CALLING YOUR STATE REPS - bit.ly/no-mask-ban Share this post with 3 friends to spread the word. Even a quick call makes a difference!
#nomaskban#noNYmaskban#CovidIsNotOver
Replied in thread
Public *
datum (n=1)

Some highlights from @ducky 's weekly roundup at covidbc.webfoot.com/2025/03/28

SARS-CoV-2 can interact with / activate the CD147 receptor to get into lymphocytes (T-cells and B-cells). (sciencedirect.com/science/arti)

women are 13.4 times more likely to get Long COVID if they are 🤰pregnant than if they are 🚫🤰not, with the danger highest if they catch COVID-19 in the third trimester. (sciencedirect.com/science/arti)

the rate of cases of postural orthostatic tachycardia syndrome (POTS) has gone up more than fourteen times compared to pre-pandemic (academic.oup.com/ehjqcco/advan)

covidbc.webfoot.com2025-03-28 General – Pandemics in British Columbia
#CovidCompetent#AirborneAware#CovidIsNotOver
Replied in thread
Public *
datum (n=1)

If you care about COVID-19 research and live in the USA, mastodon.social/@patientled/11 is highly relevant

from @patientled

@broadwaybabyto would you consider boosting patientled's post for visibility?

All slides have the Patient-Led Research Collaborative logo on the top left, illustrations of a green envelope with an arrow on it representing an email being sent, a purple telephone receiver with a couple of curved lines resembling someone calling, and a blue megaphone below with three lines representing an announcement being made. Everything is on a light-grade background. "Attention!" in bold black font. “Thanks to a swift & sustained community response, some research grants are now being restored!” Below is a thin black horizontal separator line the text under that reads, “However, the termination of the Office of Long COVID and the Advisory Committee on Long COVID remains deeply concerning, as it suggests that the administration is deprioritizing this public health crisis. We strongly urge individuals to keep taking action through the 2 initiatives on the following slides led by our partners.”
MastodonPatient-Led Research (@patientled@mastodon.social)Attached: 4 images Attention! Thanks to a swift & sustained community response, some research grants are now being restored! However, the termination of the Office of Long COVID and the Advisory Committee on Long COVID remains deeply concerning, as it suggests that the administration is deprioritizing this public health crisis. We strongly urge individuals to keep taking action through the 2 initiatives led by our partners (links in bio).
#COVID#COVID19#SARSCoV2
Public
Tom Kindlon

"Research finds potential “molecular mimics” behind #COVID -induced #autoimmune disease"

eurekalert.org/news-releases/1

“some of the human proteins the researchers identified as likely targets of COVID-induced #autoimmunity are only found in people with specific genetics”

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #Covidlonghaulers #PostCovidSyndrome @covid19 #Coronavirus
#COVID19 #COVID_19 #COVIDー19 #SARSCoV2 @novid@chirp.social #novid @novid@a.gup.pe #CovidIsNotOver
@auscovid19 #auscovid19

News Release 26-Mar-2025 Research finds potential “molecular mimics” behind COVID-induced autoimmune disease Peer-Reviewed Publication University of Utah Health COVID infection has been linked to higher risk of autoimmune disorders, including rheumatoid arthritis and type 1 diabetes. But why the virus might cause the body’s immune system to go haywire remains unknown, making it difficult to develop therapies to avoid autoimmunity. One hypothesis is that viral “molecular mimics” that resemble the body’s own proteins trigger an immune response against the virus—and healthy tissues get caught in the crossfire.
Public
Dr Joe Pajak

Over 5 years since officially recognised records of #SARSCoV2 infections in the UK - the virus that causes the disease known as COVID-19.
@ukhsa.bsky.social data provide a stark reminder of the impact of the disease.
Yet, still, there is a reticence to accept that the virus is an airborne pathogen.

Replied to Tom Kindlon
Public *
datum (n=1)

Here's another "literally brain responses are slower" result, a great one to pair with the reaction/response time slowdown, when trying to convince gamers and car drivers and sports players that COVID-19 is something to avoid:

This could suggest a form of accelerated central auditory aging in COVID-19

Our findings suggest that PASC may alter the central auditory pathway and lead to slower conduction and elevated auditory neurophysiology responses at the midbrain, a pattern associated with the typical aging process.

Notably, the younger and older groups did not differ on other dimensions of the ABR, including peak and inter-peak latencies, suggesting that heightened gain is not comorbid with deficient synaptic transmission

Delayed neural conduction time and increased central gain in the midbrain could give rise to functional cortical processing disparities in PASC

the V/I ratio increase in the PASC groups, particularly the younger subjects, potentially exceeds central changes that are expected to occur with natural aging. Indeed, in the PASC group, the younger subjects patterned similarly to the older subjects.

nature.com/articles/s41598-025

h/t the most admirable @tomkindlon

NatureAltered auditory brainstem responses are post-acute sequela of SARS-CoV-2 (PASC) - Scientific ReportsThe Post-acute Sequela of SARS-CoV-2 (PASC) syndrome, also known as Long-COVID, often presents with subjective symptoms such as brain fog and cognitive fatigue. Increased tinnitus, and decreased hearing in noise ability also occur with PASC, yet whether auditory manifestations of PASC are linked with the cognitive symptoms is not known. Electrophysiology, specifically the Auditory Brainstem Response (ABR), provides objective measures of auditory processing. We hypothesized that ABR findings would be linked to PASC and with subjective feelings of cognitive fatigue. Eighty-two individuals, 37 with PASC (mean age: 47.5, Female: 83%) and 45 healthy controls (mean age: 38.5, Female: 76%), were studied with an auditory test battery that included audiometry and ABR measures. Peripheral hearing thresholds did not differ between groups. The PASC group had a higher prevalence of tinnitus, anxiety, depression, and hearing handicap in addition to increased subjective cognitive fatigue. ABR latency findings showed a significantly greater increase in the wave V latency for PASC subjects when a fast (61.1 clicks/sec) compared to a slow click (21.1 clicks/sec) was used. The increase in latency correlated with cognitive fatigue scores and predicted PASC status. The ABR V/I amplitude ratio was examined as a measure of central gain. Although these ratios were not significantly elevated in the full PASC group, to minimize the cofounding effect of age, the cohort was median split on age. Elevated V/I amplitude ratios were significant predictors of both predicted PASC group classification and cognitive fatigue scores in the younger PASC subjects compared to age-matched controls providing evidence of elevated central gain in younger individuals with PASC. More frequent tinnitus also significantly predicted higher subjective cognitive fatigue scores. Our findings suggest that PASC may alter the central auditory pathway and lead to slower conduction and elevated auditory neurophysiology responses at the midbrain, a pattern associated with the typical aging process. This study marks a significant stride toward establishing an objective measure of subjective cognitive fatigue through assessment of the central auditory system.
#SARSCoV2#CovidIsNotOver#AirborneAware
Replied to Eric's Risk Assessment
Public *
datum (n=1)

Most interesting detail: "we detected the virus passing from one sinus at the peak of infection to the other a few days later"

Model animals: "cynomolgus macaques"

They also evaluated "two convalescent animals [...] exposed to the SARS-CoV-2 Delta variant three months prior" and found "no major uptake by the nasal cavity" but "detection of the PET signal for SARS-CoV-2 spike antigen up to three months post initial infection in the lungs and brains"

"local accumulation [...] in areas of the brain [...] consistent with previous findings of neuroinflammation in humans infected with SARS-CoV-2 and in rhesus macaques up to six weeks after SARS-CoV-2 infection. The localized crossing of the blood-brain barrier (BBB) by the radiotracer in convalescent animals can be explained by thrombo-inflammation previously reported in patients with active long-COVID."

nature.com/articles/s41467-025

h/t @EricCarroll

NatureWhole-body visualization of SARS-CoV-2 biodistribution in vivo by immunoPET imaging in non-human primates - Nature CommunicationsThere are limited approaches to monitor virus spread in vivo. Here, the authors report PET/CT-based in vivo imaging to track SARS-CoV-2 biodistribution in a COVID-19 non-human primate model using a radiolabeled human antibody revealing persistent detection in the lung and brain 3 months after infection.
#SARSCoV2#COVID19#COVID
Public
Tom Kindlon

Recording with:

- Dr David Joffe: an overview of biological basis of Long COVID

- Dr David Tuller: on basis of psycho-behavioural therapy focusing on the PACE trial & a major #LongCOVID trial"

youtu.be/V9f_kjlz6Ho

From latest Science for ME update

@longcovid
#PASC #PwLC #postcovid #postcovid19 #LC #PostCovidSyndrome #COVIDBrain #NeuroPASC
@covid19 #Coronavirus
#SARSCoV2 #CovidIsNotOver
@auscovid19 #auscovid19
@mecfs
#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MEcfs #CFS #PwME

Kirby Institute Dr David Joffe & Dr David Tuller - Is Long Covid psycho-behavioural or biological? State of evidence Recording of a recent and great talk at Kirby Institute, Australia. "In this talk, Dr David Joffe will provide an overview of the biological basis of Long COVID, while Dr David Tuller will examine the basis of psycho-behavioural therapy focusing on the PACE trial and a major Long COVID trial."
Public
N95Bias Ⓥ🏴‍☠️

“We’ve suspected for several years now that there is an association between COVID and POTS. I’m seeing this in my own clinic. My waiting list is longer than it has ever been,” said Dr. Blair Grubb, a UToledo Health cardiologist who has treated and studied POTS for more than three decades. “Now we have the data to back that up. This study helps give validity and voice to these patients, and it gives us a treatable target.”

news.utoledo.edu/index.php/03_

UToledo News | The University of Toledo News · COVID-19 Brought About a Large Rise in POTS Cases | UToledo NewsA UToledo study has found a five-fold increase in the number of newly identified postural orthostatic tachycardia syndrome patients post COVID.
#covid#covid19#SARSCoV2
Public
Tom Kindlon

From the Netherlands:

Post-COVID microvascular dysfunction in hospitalized COVID-19 survivors is associated with acute disease severity and persistent cognitive complaints

jns-journal.com/article/S0022-

From the latest Science for ME weekly update

@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC

@covid19 #Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #CovidIsNotOver
@auscovid19 #auscovid19

Journal of the Neurological Sciences Post-COVID microvascular dysfunction in hospitalized COVID-19 survivors is associated with acute disease severity and persistent cognitive complaints — Noa van der Knaap et al. "Our results provide additional evidence for microvascular damage in the [Normal Appearing White Matter], which may indicate subtle damage preceding [White Matter Hyperintensities] formation."
Public
Broadwaybabyto

As more States attempt to enact mask bans & Trump continues to dismantle public health, it becomes increasingly clear that we’re on our own.

Masks should be mandatory in healthcare, yet you will often see more patients masking than healthcare workers.

My guide to avoiding hospital acquired COVID

disabledginger.com/p/how-to-st

The Disabled Ginger · How to Stay Covid Safe When in HospitalBy Broadwaybabyto
#covidisairborne#covidisnotover#longcovid
Public
:asan_green: ΘΔ

another #NorthCarolina group looking to make public events safer through COVID activism!

queer the air collective is a QTBIPOC mutual aid group based out of "durham, NC" 😷 🌈

besides their work on COVID education on centralized social media...

they opened up a lending library, where they loan an air purifier (currently one so far) for free to community events in the triangle. they have a fundraiser, where they hope to buy more air purifiers to lend out to more events & happenings to make public spaces safer for all!

givebutter.com/qtacollective

Queer the Air CollectiveLaunching the Queer the Air CollectiveCleaning the air in the Triangle one air purifier at a time.
#COVID#COVID19#SARS
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