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#insulin

1 post1 participant0 posts today
Public
Chris Geoghooligan

Attn: #T1D folks.

Have you any experience with #fiasp, particularly as used in an #insulin pump? How does it compare to #humalog or #novolog?

I take #novolog via my #tandem #tslim, but I’m finding it increasingly difficult to control my BG as my #gastroparesis grows more erratic over time. I’m wondering if a faster-acting insulin might help, allowing me to NOT bolus until I see a BG rise when my stupid stomach decides to start digesting (sometimes immediately, sometimes 4 hours later).

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szakib

A new Hungarian study found that #mushrooms help with #insulin resistance.

#diabetes #medicine

mdpi.com/1422-0067/26/2/827

MDPIThe Importance of Edible Medicinal Mushrooms and Their Potential Use as Therapeutic Agents Against Insulin ResistanceIn addition to conventional treatments, there is growing interest in preventive and complementary therapies. Proper nutrition can prevent the manifestation of several chronic diseases such as obesity, diabetes, cardiovascular disease, and cancer, and can attenuate the severity of these diseases. Edible mushrooms have been used as nutrition and medicine for thousands of years. The spectrum and quantity of their medicinal compounds made them a widely investigated target both in basic research and clinical trials. The most abundant and medically important components are polysaccharides, terpenoids, phenols, and heterocyclic amines, but bioactive proteins, vitamins, including vitamin D, polyunsaturated fatty acids, and essential minerals are also important ingredients with noteworthy health benefits. Mushroom extracts have anti-diabetic, anti-hyperlipidemic, anti-inflammatory, antioxidant, cardioprotective, anti-osteoporotic, and anti-tumor effects and are well tolerated, even by cancer patients. In our previous review we detailed the molecular aspects of the development of type 2 diabetes, discussing the role of physical activity and diet, but we did not detail the role of medicinal mushrooms as part of nutrition. In this review, we aimed to summarize the most important medical mushrooms, along with their natural habitats, growing conditions, and components, that are presumably sufficient for the prevention and treatment of insulin resistance.
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Malvan

Efter sonens insjuknande i diabetes tänker jag mycket på vilken beredskap "vi" (Sverige?) har gällande insulinproduktion. Vad händer om det blir krig/kris? Vem reglerar detta, finns det nåt åtagande, läkemedelsverket? (utlagt på kommersiella företag isf antar jag) Kan jag sätta upp en egen produktion ... hur tillverkas insulin 😥

#diabetes#t1d#insulin
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KB Sez

Dear diabetics: do you know anybody in your life, family or circles who voted for #Trump?

I hope you’re keeping a list of all of them and I hope that you go out of your way to ‘thank’ them for this increase in the cost of insulin and be sure and tell everyone you know that they are the ones who voted for him and voted for this .

If you voted for him, you are getting what you voted for. You have no one to blame but yourself.

#Insulin #Diabetic

From: @grrlscientist
mastodon.social/@grrlscientist

MastodonGrrlScientist ⧖ Ⓥ (@grrlscientist@mastodon.social)Attached: 1 image All 3 #insulin makers have announced price increases ranging from 2000-3000% after the orange jesus rescinded Biden’s Executive Order 14087 curbing #DrugPrices. “Sick people need to pay their own way, I mean what’s wrong with them anyway?” he said. um ... they're SICK?? #BigPharma #politics
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BedastGPT

Humalog and Lyumjev are both lispro insulins. The difference is the acid used in Lyumjev to stimulate blood flow at the injection site for faster absorption.

Often, this is not noticed with pen injections. But in a pump, where there’s a relatively continuous infusion and occasional bolus infusions at the same place, Lyumjev can become painful.

Some people adjust to it. I have not.

Those who like the performance of Lyumjev but find it too uncomfortable to use in an insulin pump might try mixing Humalog and Lyumjev to reduce the bite. I know of one person that does a 1:1 ratio of the two, and another person who does 3:1 Humalog to Lyumjev (25% Lyumjev).

I am using a 3:1 mix right now. It feels like full strength Lyumjev.

My first go with Humalog was just 100% Humalog so I could assess how I respond to it. There was no pain. In fact, I didn’t feel boluses at all. I did notice the difference in timing, but it was super minor and easy to adjust to.

Even though I am now no longer planning to mix Lyumjev and Humalog, this was still a successful experiment because I learned something. And that’s good! I now have a path forward with my insulin use, and honestly, keeping it simple with something I’m pretty sure will work fine feels a bit better anyway.

One thing I’ve learned in the management of my illnesses is experimentation to find the best management is part of it.

#Diabetes#Insulin#Humalog
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BedastGPT

Today I started using Humalog in my pump. Lyumjev was a bit rough.

Just did my first bolus after several hours of just basal rate. I didn’t feel it. No irritation. It was almost 9U total.

Now I just need a good reliable CGM and this will be probably as good a pump experience as I can get.

#Diabetes#Tandem#Mobi
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Benjamin Carr, Ph.D. 👨🏻‍💻🧬

#Sana’s cell therapy may be ‘transformative cure’ for type 1 #diabetes
#Biotech is evaluating UP421, donor-derived allogeneic primary islet cell therapy, as #T1D treatment that doesn’t require #immunosuppression. Four weeks after cells were transplanted into patient’s arm, therapy had avoided immune rejection and was tied to consistent levels of c-peptide expression—a biomarker that indicates if the transplanted beta cells are producing #insulin.
fiercebiotech.com/biotech/sana
archive.ph/dT0Vd

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J. Steven York RESISTS

Update on the insulin situation. I had a new prescription for a different insulin Monday morning. I was able to pick it up a couple hours later and immediately get my daily shot, about ten hours late, which isn't critical for me. No problems so far, and I like the functionality of the injector pen much better than the old Novo Nordisk one, which was cranky and sometimes difficult to inject, even for a guy with big, fairly strong, hands.

#usHealthCare#novoNordisk#insulin
Continued thread
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J. Steven York RESISTS

So why, you ask, was Levimir discontinued? Maker Novo Nordisk got upset about insulin price laws and decided they could make more money making Ozempic (which ironically I ALSO take, for diabetes, not for weight loss). Why is access to insulin seemingly controlled as much (or more) than opioids? I suspect it's because of rules and state laws that were likely written by big-pharma lobbyists to control the trade.
#usHealthCare #pharma #novoNordisk #insulin #diabetes #ozempic #levimir

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J. Steven York RESISTS

Discontinued insulin update: Got a call back from Urgent Care. Absolutely NOTHING can be done before Monday (Small, isolated town, limited medical resources) before Monday unless I go to the emergency room (on a busy saturday night in a tourist town), wait forever in Covid Town, and pay a $100 copay for other people's incompetence. I'll skip my Sunday night shot and hope i can get it fixed before too late on monday.
#diabetes #usmedicalcare #NovoNordisk #insulin

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