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#biology

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Novel Delta Receptor Drug Offers Safer Pain Relief

Summary: In a study by the University of Florida, a novel drug compound activating delta opioid receptors promises safer pain relief, avoiding traditional opioids' side effects like respiratory depression and addiction. This could revolutionize treatment, emphasizing urgency for safer, effective pain management.

Read More:
https://biohackers.media/novel-delta-receptor-drug-offers-safer-pain-relief

#health #science #biology @science@lemmy.world @news@lemmy.world @health@lemmy.world

Biohackers Media · Novel Delta Receptor Drug Offers Safer Pain ReliefNovel drug compound activates delta opioid receptors for effective pain relief with fewer side effects, offering a safer alternative to opioids.

GLP-1 Agonists Linked to Reduced Dementia Risk

Summary: A study by University of Galway students highlights a 45% dementia risk reduction with GLP-1 receptor agonists, offering potential for diabetes medications to benefit cognitive health. Published in JAMA Neurology, it underscores the need for further research on neuroprotective effects.

Read More:
https://biohackers.media/glp-1-agonists-linked-to-reduced-dementia-risk

#health #science #biology @science@lemmy.world @news@lemmy.world @health@lemmy.world

Factors Affecting Seniors' Active Life Expectancy

Summary: The study emphasizes age-related risks for disability and the impact of hospitalizations on active life expectancy. Understanding hospitalization types, preventative measures, and patient interventions can enhance functional independence among older adults.

Read More:
https://biohackers.media/factors-affecting-seniors-active-life-expectancy

#health #science #biology @science@lemmy.world @news@lemmy.world @health@lemmy.world

IL1α Boosts Liver Organoid Growth in Hypoxia

Summary: Researchers at The University of Tokyo found placenta-derived IL1α significantly enhances human liver organoid growth under hypoxic conditions, growing up to five times larger. This breakthrough, published in Nature Communications, could advance organoid scalability and functionality in regenerative medicine.

Read More:
https://biohackers.media/il1a-boosts-liver-organoid-growth-in-hypoxia

#health #science #biology @science@lemmy.world @news@lemmy.world @health@lemmy.world

Biohackers Media · IL1α Boosts Liver Organoid Growth in HypoxiaIL1α boosts human liver organoid growth under hypoxic conditions, advancing regenerative medicine, per The University of Tokyo study.

Measuring Mucus by Dragging Dead Fish

A fish‘s mucus layer is critical; it protects from pathogens, reduces drag in the water, and, in some cases, protects against predators. But little is known about how mucus could affect terrestrial locomotion in species like the northern snakehead, which can breathe out of the water and move across land. So researchers explored the snakehead’s mucus layer by measuring the force required to drag them (and two other non-terrestrial species) across different surfaces.

The team tested the same, freshly euthanized fish twice: once with its mucus layer intact and again once the mucus was washed off. Unsurprisingly, the fish’s friction was much lower with its mucus. But they also found that the snakehead was slipperier than either the scaled carp or the scale-free catfish. The biologists suggest that the snakehead could have evolved a slipperier mucus to help it move more easily on land, thereby extending the distance it can cover.

As a fluid dynamicist, I think fish mucus sounds like a great new playground for the rheologists among us. (Image and research credit: F. Lopez-Chilel and N. Bressman; via PopSci)

For #academia #biology

I started a part-time job at NYMC sequencing core past Oct. PI here (Ravi Sachidanandam) didn't pay me until late Jan, and is now arguing I shouldn't be paid for earlier period since I wasn't present full-time.

And now it looks like 'official' job contract only covers work from late November onward and he was just lying about backpay.

I don't even care about the money - but I would like to get a warning out there about this lab. What would be a good way for this?