Pathoblockers are different from #antibiotics - they work specifically to halt the pathogenicity or infectiousness of a microbe.

#health #medicine #research #science #biology

https://www.labroots.com/trending/microbiology/28871/type-drug-fight-salmonella-pathoblocker

New gonorrhoea treatment hailed as breakthrough in fight against drug resistance https://www.theguardian.com/society/2025/apr/14/new-gonorrhoea-treatment-gepotidacin-hailed-breakthrough-drug-resistance #Medicalresearch #Drugresistance #Sexualhealth #Antibiotics #Gonorrhoea #Worldnews #Science #Society #Health #Women

Three million child deaths linked to drug resistance
https://www.bbc.com/news/articles/cy0xk86l9g9o

"Experts say this new study highlights a more than tenfold increase in AMR-related infections in children in just three years."

Saccharine disrupts bacterial membranes and inhibits bacterial growth, and so can be an effective antimicrobial alone and in conjunction with antibiotic drugs.

Summary: https://phys.org/news/2025-04-artificial-sweetener-power-antibiotic-resistance.html

Original paper: https://www.embopress.org/doi/full/10.1038/s44321-025-00219-1

New publication: Total Synthesis, Structure Elucidation, and Bioactivity Evaluation of the Cyclic #Lipopeptide Natural Product #PaenilipoheptinA,. #bacteria #antibiotics #pharmaceuticals
https://doi.org/10.1021/acs.orglett.5c00232

"This is a new molecule with a new mode of action," said senior study author Gerry Wright, a professor at McMaster University, among other appointments. "It's a big leap forward for us."

#antibiotics #microbiology #medicine #health #research #science

https://www.labroots.com/trending/cell-and-molecular-biology/28770/lariocidin-class-antibiotics-discovered

New drug for lower back pain could be ‘a gamechanger’ https://www.theguardian.com/society/2025/mar/28/new-drug-for-lower-back-pain-could-be-a-gamechanger #Medicalresearch #Antibiotics #Backpain #Science #Society #Drugs

Swedish stakeholders harbour CMA competition concerns: Swedish stakeholders have broadly welcomed the CMA, but some question its competition mechanics and the import dynamics for narrow-spectrum #antibiotics and cancer medicines. https://www.euractiv.com/section/health-consumers/news/swedish-stakeholders-harbour-cma-competition-concerns/?utm_source=mastodon&utm_medium=dlvr.it

Antimicrobial resistance poses a growing threat, with over 2.8 million resistant infections in the U.S. annually. Researchers are using advanced genetic analysis to track how microbes evolve to evade #antibiotics. A microbiologist explains: https://buff.ly/JJCWYWU

Rare, but potentially fatal: #WhipplesDisease is a bacterial infection that requires prompt antibiotic treatment. Currently, guidelines recommend infusions in the hospital. But as a #CharitéBerlin study now shows, taking tablets at home is just as effective.

Find out more in our Paper spotlight https://www.charite.de/en/research/paper_spotlight/new_findings_on_the_treatment_of_whipples_disease

Doctors’ best friends: dogs will help sniff out bacteria for cystic fibrosis sufferers https://www.theguardian.com/society/2025/mar/22/dogs-will-help-sniff-out-bacteria-cystic-fibrosis-sufferers #ImperialCollegeLondon #Medicalresearch #Cysticfibrosis #Antibiotics #Science #Animals #Society #Dogs

The Evolution of Bacteria on a “Mega-Plate” Petri Dish (2016) https://www.youtube.com/watch?v=plVk4NVIUh8 #antibiotics #resistance #wereallgoingtodie #microbiology #visualization

Microplastics could be fueling antibiotic resistance https://www.sciencedaily.com/releases/2025/03/250311121511.htm

UK scientists develop DNA sequencing system to fight superbugs https://www.theguardian.com/society/2025/mar/06/uk-scientists-develop-dna-sequencing-system-to-fight-superbugs #MRSAandsuperbugs #Antibiotics #Hospitals #Society #Science #Health #NHS

#FYI #microplastics #pollution #environmentalpollution #antibiotics #antibioticresistance #antimicrobialresistance

"microplastics in the environment increase antibiotic resistance by up to 200 times"

Good morning, everybody!

https://www.soci.org/news/2025/1/antimicrobial-resistance-how-microplastics-can-increase-the-spread-of-amr

The original article, open access:

Yang et al. 2025 Environ Int 195: 109261
https://doi.org/10.1016/j.envint.2025.109261

Forget Covid - this is scarier

AMR is already contributing to more than 35,000 deaths a year in the UK, estimates suggest. But the government “remains a long way” from achieving its aim of containing and controlling AMR, the National Audit Office (NAO) said.

If action is not taken to stem the crisis, the consequences for health, life expectancy, the functioning of the NHS and the wider economy would be “huge”.

https://www.theguardian.com/society/2025/feb/26/uk-falling-short-in-fight-against-rise-of-superbugs-resistant-to-antibiotics

UK ‘falling short’ in fight against rise of superbugs resistant to antibiotics https://www.theguardian.com/society/2025/feb/26/uk-falling-short-in-fight-against-rise-of-superbugs-resistant-to-antibiotics #Antibiotics #Politics #Society #Health #UKnews #NHS

Yes, Imitation Meat Is Processed. Can It Also Be #Healthy?
After being targeted by the meat industry, swept up in the culture wars and pummeled in sales, two #plantbased meat companies are reinventing themselves.
Plant based meat is ultraprocessed, but not necessarily unhealthy, according to several experts. The products generally have less saturated fat, no cholesterol and more fiber than animal meat, and zero #hormones or #antibiotics.
https://www.nytimes.com/2025/01/16/climate/plant-based-meat-processed-foods.html
https://archive.ph/3Ym0C

Key drivers of dietary impacts of Swedish #children – for #carbon footprint, #landuse, phosphorus & #nitrogen inputs, blue #water, ammonia #emissions, #pesticide use, #biodiversity loss, #antibiotics use, and #animalwelfare – were red #meat & #dairy products… (1/x) https://doi.org/10.1016/j.crsust.2025.100281